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References Suggestions


Standard Name


Gene Synonym(s)

ECK0187, b0188, JW0183, mesJ, yaeN[1], yaeN

Product Desc.


tRNA(Ile) lysidine (L34) synthase, ATP-dependent; solely responsible for tRNA(Ile) lysidine 34 (L34) formation[4]

Product Synonyms(s)

tRNA(Ile)-lysidine synthetase[1], B0188[2][1], YaeN[2][1], MesJ[2][1], TilS[2][1] , ECK0187, JW0183, mesJ, yaeN, b0188

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): tilS[2]

Quick Links

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YaeN (TilS) is mistakenly labeled as a cell cycle gene in many databases. the confusion arose from the misinterpretation of Genbank Z50870. the real "minE suppressor" is the small rof gene next to tilS, labeled as orf4 in Z50870. PDB: 1NI5. Gu M., Burling T., Lima C.D., Structure of the MesJ PP-ATPase from Escherichia coli, unpublished. tilS is an essential gene. AFMB Structural Genomics target No. 121 (http://afmb.cnrs-mrs.fr/article171.html).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.