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References Suggestions


Standard Name


Gene Synonym(s)

ECK0088, b0087, JW0085, murX[1], murX

Product Desc.

UDP-N-acetylmuramoyl-pentapeptide:undecaprenyl-PO4 phosphatase[2]

Product Synonyms(s)

phospho-N-acetylmuramoyl-pentapeptide transferase[1], B0087[3][1], MurX[3][1], MraY[3][1] , ECK0088, JW0085, murX, b0087

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): mraZW-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ[3]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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The aspartic acid residues DD115, D116, and D267 are necessary for catalysis. The model suggested indicates that D115 and D116 chelate the Mg2+ cofactor, which in turn binds the pyrophosphate bridge of the UDP-MurNAc-pentapeptide, and D267 acts as the catalytic nucleophile.[2]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. 3.0 3.1 3.2 3.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7