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References Suggestions


Standard Name


Gene Synonym(s)

ECK0052, b0051, JW0050, rsmA, ksgA[1][2], ksgA

Product Desc.

S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase[3][2]

16S rRNA dimethyladenosine transferase; S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; mutant is kasugamycin resistant; multicopy suppressor of era(Cs)[4]

Product Synonyms(s)

S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase[1], B0051[3][1], KsgA[3][1], RsmA[3][1] , ECK0052, JW0050, ksgA, b0051

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): pdxA-rsmA[3], pdxA-rsmA, pdxA-rsmA-apaGH[3], pdxA-rsmA-apaG-apaH, rsmA-apaGH[3], rsmA-apaG-apaH, rsmA-apaG-apaH, surA-pdxA-rsmA-apaGH[3], surA-pdxA-rsmA-apaGH

Quick Links


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KsgA dimethylates two adjacent 16S rRNA adenosines. ksgA deletion mutants grow more slowly than an isogenic wt at 20C (Connolly, 2008).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.