PMID:9988468

Citation	Humayun, MZ (1998) SOS and Mayday: multiple inducible mutagenic pathways in Escherichia coli. Mol. Microbiol. 30:905-10
Abstract	Environmental and physiological stress conditions can transiently alter the fidelity of DNA replication. The DNA damage-mediated SOS response in Escherichia coli is the best-known example of such an 'inducible mutagenesis' or 'transient mutator' pathway. Emerging evidence suggests the existence of a number of other stress-inducible pathways that also affect the fidelity of replication. Among the more provocative recent findings are UVM, an SOS-independent damage-inducible mutagenic pathway, and a new recA-dependent but umuD/C-independent pathway that appears to be provoked by translational stress. These findings alter our view of inducible mutagenesis, and anticipate the existence of previously unrecognized links between protein synthesis and DNA replication.
Links	PubMed
Keywords	Bacterial Proteins/genetics; DNA Replication; DNA-Directed DNA Polymerase/metabolism; Escherichia coli/genetics; Escherichia coli Proteins; Mutagenesis; Protein Biosynthesis; Rec A Recombinases/genetics; SOS Response (Genetics); Ultraviolet Rays
edit table

Significance

You can help EcoliWiki by summarizing why this paper is useful

You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.

Add links to pages that link here (e.g. gene, product, method pages)

See Help:References for how to manage references in EcoliWiki.