PMID:9889164
| Citation |
Zhang, L, Godzik, A, Skolnick, J and Fetrow, JS (1998) Functional analysis of the Escherichia coli genome for members of the alpha/beta hydrolase family. Fold Des 3:535-48 |
|---|---|
| Abstract |
Database-searching methods based on sequence similarity have become the most commonly used tools for characterizing newly sequenced proteins. Due to the often underestimated functional diversity in protein families and superfamilies, however, it is difficult to make the characterization specific and accurate. In this work, we have extended a method for active-site identification from predicted protein structures. |
| Links | |
| Keywords |
Amino Acid Sequence; Databases, Factual; Escherichia coli/genetics; Genome, Bacterial; Hydrolases/chemistry; Hydrolases/genetics; Molecular Sequence Data; Predictive Value of Tests; Protein Folding |
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