PMID:9873406
| Citation |
Gegnas, LD, Waddell, ST, Chabin, RM, Reddy, S and Wong, KK (1998) Inhibitors of the bacterial cell wall biosynthesis enzyme MurD. Bioorg. Med. Chem. Lett. 8:1643-8 |
|---|---|
| Abstract |
A series of transition-state analog inhibitors of the D-glutamic acid-adding enzyme (MurD) of bacterial peptidoglycan biosynthesis has been synthesized and evaluated for inhibition of the E. coli enzyme. |
| Links | |
| Keywords |
Cell Wall/enzymology; Escherichia coli/enzymology; Molecular Structure; Organophosphorus Compounds/chemistry; Peptide Synthases/antagonists & inhibitors; Peptide Synthases/chemistry |
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