PMID:9717214

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Citation

Andersson, SG and Kurland, CG (1998) Reductive evolution of resident genomes. Trends Microbiol. 6:263-8

Abstract

Small, asexual populations are expected to accumulate deleterious substitutions and deletions in an irreversible manner, which in the long-term will lead to mutational meltdown and genome decay. Here, we discuss the influence of such reductive processes on the evolution of genomes that replicate within the domain of a host genome.

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Keywords

Animals; Bacteria/genetics; Evolution, Molecular; Genome; Mutation; Recombination, Genetic

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