PMID:9685179
| Citation |
Chatterji, D, Fujita, N and Ishihama, A (1998) The mediator for stringent control, ppGpp, binds to the beta-subunit of Escherichia coli RNA polymerase. Genes Cells 3:279-87 |
|---|---|
| Abstract |
Inhibition of transcription of rRNA in Escherichia coli upon amino acid starvation is thought to be due to the binding of ppGpp to RNA polymerase. However, the nature of this interaction still remains obscure. |
| Links | |
| Keywords |
Binding Sites; Chromatography, Gel; Chromatography, Thin Layer; DNA-Directed RNA Polymerases/metabolism; Escherichia coli/genetics; Escherichia coli/metabolism; Guanosine Tetraphosphate/analogs & derivatives; Guanosine Tetraphosphate/metabolism; Guanosine Tetraphosphate/pharmacology; Ligases/metabolism; Photoaffinity Labels; Protein Denaturation; Ribosomal Proteins/genetics; Time Factors; Transcription, Genetic/drug effects; Trypsin; rRNA Operon/genetics |
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