PMID:9663656

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Citation

Ishioka, K, Fukuoh, A, Iwasaki, H, Nakata, A and Shinagawa, H (1998) Abortive recombination in Escherichia coli ruv mutants blocks chromosome partitioning. Genes Cells 3:209-20

Abstract

All the ruvA, ruvB and ruvC mutants of Escherichia coli are sensitive to treatments that damage DNA, and are mildly defective in homologous recombination. It has been reported that the ruv mutants form nonseptate, multinuclear filaments after low doses of UV irradiation, dependent on the sfiA gene product. In vitro, the RuvAB complex promotes the branch migration of Holliday junctions, and RuvC resolves the junctions endonucleolytically.

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Keywords

Adenosine Triphosphatases/genetics; Bacterial Proteins/genetics; Chromosomes, Bacterial; DNA Helicases/genetics; DNA Polymerase I/genetics; DNA Repair; DNA-Binding Proteins/genetics; Endodeoxyribonucleases/genetics; Escherichia coli/genetics; Escherichia coli/radiation effects; Escherichia coli/ultrastructure; Escherichia coli Proteins; Exodeoxyribonuclease V; Exodeoxyribonucleases/genetics; Models, Genetic; Mutation; Rec A Recombinases/genetics; Recombination, Genetic; Ultraviolet Rays

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