PMID:9382825
| Citation |
Eggleston, AK and West, SC (1997) Recombination initiation: easy as A, B, C, D... chi? Curr. Biol. 7:R745-9 |
|---|---|
| Abstract |
The octameric Chi (chi) sequence is a recombination hotspot in Escherichia coli. Recent studies suggest a singular mechanism by which chi regulates not only the nuclease activity of RecBCD enzyme, but also the ability of RecBCD to promote loading of the strand exchange protein, RecA, onto chi-containing DNA. |
| Links | |
| Keywords |
Binding Sites; DNA, Bacterial/genetics; Escherichia coli/genetics; Exodeoxyribonuclease V; Exodeoxyribonucleases/metabolism; Mutation; Rec A Recombinases/metabolism; Recombination, Genetic |
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