PMID:9368371

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Citation

Vica Pacheco, S, García González, O and Paniagua Contreras, GL (1997) The lom gene of bacteriophage lambda is involved in Escherichia coli K12 adhesion to human buccal epithelial cells. FEMS Microbiol. Lett. 156:129-32

Abstract

The role of the lom gene of bacteriophage lambda in adhesion of Escherichia coli to human buccal epithelial cells (HBC) was studied testing the adherence of lamda lom+ and lambda lom::TnphoA E. coli lysogens. lambda lom+ prophage increased 50% E. coli adhesion. This effect was not observed with lambda lom::TnphoA. These results suggest that the normal Lom protein participates directly in adhesion or regulates the synthesis of other protein(s), which may be involved in adhesion.

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Keywords

Adult; Bacterial Adhesion/genetics; Bacterial Outer Membrane Proteins/genetics; Bacteriophage lambda/genetics; Cheek/microbiology; Epithelial Cells/microbiology; Escherichia coli/genetics; Escherichia coli/pathogenicity; Escherichia coli/virology; Genes, Viral; Humans; Viral Proteins; Virulence/genetics

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