PMID:9366549

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Citation

Kusano, S and Ishihama, A (1997) Functional interaction of Escherichia coli RNA polymerase with inorganic polyphosphate. Genes Cells 2:433-41

Abstract

RNA polymerase from the stationary growth phase cells of Escherichia coli is tightly associated with an acidic compound(s) and exhibits altered promoter selectivity, with reduced transcriptional activity of the genes highly expressed in the exponentially growing cells. Here we have examined the nature of the RNA polymerase-associated acidic compound(s).

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Keywords

Chromatography; DNA-Directed RNA Polymerases/physiology; Drug Interactions; Escherichia coli/enzymology; Polyphosphates/metabolism; Polyphosphates/pharmacology; Promoter Regions, Genetic/drug effects; Promoter Regions, Genetic/physiology; Transcription, Genetic

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