PMID:9327573
| Citation |
Ness, LS, Ferguson, GP, Nikolaev, Y and Booth, IR (1997) Survival of Escherichia coli cells exposed to iodoacetate and chlorodinitrobenzene is independent of the glutathione-gated K+ efflux systems KefB and KefC. Appl. Environ. Microbiol. 63:4083-6 |
|---|---|
| Abstract |
The KefB and KefC systems of Escherichia coli cells are activated by iodoacetate (IOA) and chlorodinitrobenzene (CDNB), leading to a rapid drop in the intracellular pH. However, survival of exposure to IOA or CDNB was found to be essentially independent of KefB and KefC activation. No correlation was found between the toxicity of the compound and its ability to elicit protective acidification via activation of KefB and KefC. |
| Links | |
| Keywords |
Antiporters/metabolism; Bacterial Proteins/metabolism; Cell Division/drug effects; Dinitrochlorobenzene/pharmacology; Dinitrochlorobenzene/toxicity; Escherichia coli/drug effects; Escherichia coli/growth & development; Escherichia coli/metabolism; Escherichia coli Proteins; Glutathione/metabolism; Hydrogen-Ion Concentration; Iodoacetates/pharmacology; Iodoacetates/toxicity; Iodoacetic Acid; Ion Channel Gating; Ion Transport/drug effects; Potassium Channels/metabolism; Potassium-Hydrogen Antiporters |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
See also
References
See Help:References for how to manage references in EcoliWiki.