PMID:9315294
| Citation |
Kałuzna, A and Bartosz, G (1997) Transport of glutathione S-conjugates in Escherichia coli. Biochem. Mol. Biol. Int. 43:161-71 |
|---|---|
| Abstract |
There are no reports concerning glutathione-S-conjugates transport in prokaryotic cells, although many studies have been performed in eukaryotic systems. This study demonstrates that glutathione S-conjugates (2,4-dinitrophenyl-S-glutathione and bimane-S-glutathione) are transported also out of Escherichia coli K12 cells. This transport is inhibited by vanadate, fluoride and other inhibitors of glutathione S-conjugate transport in mammalian cells suggesting a similarity of this process to that known in eukaryotes. |
| Links | |
| Keywords |
Bicyclo Compounds/metabolism; Biological Transport, Active/drug effects; Escherichia coli/drug effects; Escherichia coli/metabolism; Fluorides/pharmacology; Glutathione/analogs & derivatives; Glutathione/metabolism; Kinetics; Probenecid/pharmacology; Uncoupling Agents/pharmacology; Vanadates/pharmacology |
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