PMID:9294462
| Citation |
Tao, K (1997) oxyR-dependent induction of Escherichia coli grx gene expression by peroxide stress. J. Bacteriol. 179:5967-70 |
|---|---|
| Abstract |
The Escherichia coli OxyR protein is a transcriptional activator for a number of genes induced in response to low concentrations of hydrogen peroxide. To identify additional OxyR-regulated genes, I cloned a DNA fragment that shows promoter activity regulated by OxyR by direct selection of OxyR-binding DNA fragments. Analyses of the cloned fragment indicate that the grx gene, encoding glutaredoxin 1, is inducible by hydrogen peroxide in an oxyR-dependent fashion. |
| Links | |
| Keywords |
Base Sequence; Binding Sites; DNA-Binding Proteins; Enzyme Induction; Escherichia coli/genetics; Escherichia coli Proteins; Gene Expression Regulation, Bacterial/drug effects; Gene Expression Regulation, Enzymologic/drug effects; Glutaredoxins; Hydrogen Peroxide/pharmacology; Molecular Sequence Data; Oxidoreductases; Proteins/genetics; RNA, Bacterial/biosynthesis; Repressor Proteins/genetics; Restriction Mapping; Transcription Factors/genetics; Transcription, Genetic |
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