PMID:9260970
| Citation |
Jovanovic, G, Dworkin, J and Model, P (1997) Autogenous control of PspF, a constitutively active enhancer-binding protein of Escherichia coli. J. Bacteriol. 179:5232-7 |
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| Abstract |
Escherichia coli sigma54-dependent phage shock protein operon (pspA to -E) transcription is under the control of PspF, a constitutively active activator. Sigma70-dependent transcription of pspF is under autogenous control by wild-type PspF but not by a DNA-binding mutant, PspF deltaHTH. Negative autoregulation of PspF is continual and not affected by stimuli, like f1 pIV, that induce the pspA to -E operon. PspF production is independent of PspA (the negative regulator of the pspA to -E operon) and of PspB and -C (positive regulators). |
| Links | |
| Keywords |
Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Enhancer Elements, Genetic; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Heat-Shock Proteins/genetics; Heat-Shock Proteins/metabolism; Operon; Regulatory Sequences, Nucleic Acid; Trans-Activators/genetics; Trans-Activators/metabolism; Transcription, Genetic |
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