PMID:9246756

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Citation

D'Ari, R (1997) The Escherichia coli cell cycle, cell division and ppGpp: regulation and mechanisms. Folia Microbiol. (Praha) 42:161-4

Abstract

The literature demonstrating tight regulation of the Escherichia coli cell cycle is reviewed. Recent evidence is presented indicating that the normal rod cell shape can be abandoned, allowing growth as a coccus, either by increasing the amount of the division proteins FtsZ, FtsA and FtsQ, or by increasing the pool of the nucleotide ppGpp. It is argued that ppGpp may be a cell cycle signal in E. coli.

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Keywords

Cell Cycle/physiology; Escherichia coli/cytology; Escherichia coli/growth & development; Guanosine Tetraphosphate/metabolism; Models, Genetic

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