PMID:9157486
| Citation |
Kleerebezem, M, Heutink, M, de Cock, H and Tommassen, J (1996) The qmeA (ts) mutation of Escherichia coli is localized in the fabI gene, which encodes enoyl-ACP reductase. Res. Microbiol. 147:609-13 |
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| Abstract |
The phenotypes of temperature-sensitive qmeA and fabI mutants of Escherichia coli appear to be very similar. Furthermore, the qmeA mutation could be complemented by the fabI gene on a plasmid, and the fabI allele derived from the qmeA mutant strain harbours a nucleotide substitution identical to that from a previously characterized fabI mutant. These results show that the qmeA gene is, in fact, identical to the fabI gene, which encodes enoyl-ACP reductase, involved in fatty acid elongation. |
| Links | |
| Keywords |
Enoyl-(Acyl-Carrier Protein) Reductase (NADPH, B-Specific); Escherichia coli/enzymology; Escherichia coli/genetics; Genes, Bacterial/genetics; Mutation; Oxidoreductases/genetics; Oxidoreductases/metabolism; Phenotype |
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