PMID:9037114

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Citation

Wachi, M, Umitsuki, G and Nagai, K (1997) Functional relationship between Escherichia coli RNase E and the CafA protein. Mol. Gen. Genet. 253:515-9

Abstract

We analyzed the functional relationship between the Escherichia coli RNase E and the CafA protein, which show extensive sequence similarity. The temperature-sensitive growth of the RNase E mutant strain ams1 was partially suppressed by multicopy plasmids bearing the cafA gene. Introduction of a cafA::cat mutation enhanced the temperature sensitivity of the ams1 mutant. These results suggest that there is a functional homology between these two proteins.

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Keywords

Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Bacterial Proteins/physiology; Endoribonucleases/chemistry; Endoribonucleases/genetics; Endoribonucleases/physiology; Escherichia coli/enzymology; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli/physiology; Escherichia coli Proteins; Genes, Bacterial; Mutagenesis, Insertional; Temperature

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