PMID:8996790

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Citation

Rosenblueth, DA, Thieffry, D, Huerta, AM, Salgado, H and Collado-Vides, J (1996) Syntactic recognition of regulatory regions in Escherichia coli. Comput. Appl. Biosci. 12:415-22

Abstract

One of the most common methodologies to identify cis-regulatory sites in regulatory regions in the DNA is that of weight matrices, as testified by several articles in this issue. An alternative to strengthen the computational predictions in regulatory regions is to develop methods that incorporate more biological properties present in such DNA regions. The grammatical implementation presented in this paper provides a concrete example in this direction.

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Keywords

Algorithms; Base Sequence; DNA, Bacterial/analysis; Escherichia coli/genetics; False Positive Reactions; Programming Languages; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid

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