PMID:8944892
| Citation |
Yariv, J (1996) Circumstantial evidence for cytochrome b1 involvement in the functioning of lac-permease in respiring Escherichia coli. J. Theor. Biol. 182:459-62 |
|---|---|
| Abstract |
The structure of the haem-binding site of cytochrome b1 and particularly the fact that the two protein ligands of the haem are methionines could explain a correlation found between loss of lac-permease activity and replacement of methionine by norleucine in the protein of aerobically respiring E. coli. If cytochrome b1 is essential for lac-permease mediated transport in whole bacteria as this correlation suggests, translocation of substrate by this permease must be coupled to electron transport. Such a dependence would invalidate the chemiosmotic interpretation of lactose transport in E. coli in its present form and would be in variance with the coupling-by-energy theories of lactose transport that exempted translocation from dependence on energy yielding processes. |
| Links |
PubMed Online version:10.1006/jtbi.1996.0187 |
| Keywords |
Bacterial Proteins; Biological Transport, Active; Cytochrome b Group/metabolism; Enzyme Activation; Escherichia coli/metabolism; Escherichia coli Proteins; Ferritins/metabolism; Lactose/metabolism; Membrane Transport Proteins/metabolism; Methionine/metabolism; Monosaccharide Transport Proteins; Oxygen Consumption; Symporters |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.