PMID:8824175

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Citation

Ramseier, TM, Chien, SY and Saier, MH Jr (1996) Cooperative interaction between Cra and Fnr in the regulation of the cydAB operon of Escherichia coli. Curr. Microbiol. 33:270-4

Abstract

In vivo and in vitro experiments are reported demonstrating that the catabolite repressor-activator (Cra) protein (formerly designated FruR) regulates expression of the cydAB operon of Escherichia coli encoding cytochrome d oxidase. The Fnr protein is required for Cra-mediated transcriptional control, but the ArcA protein antagonizes the response to Cra. The results establish that Fnr, ArcA, and Cra exert their effects in an interdependent fashion.

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Keywords

Bacterial Outer Membrane Proteins/metabolism; Bacterial Proteins/antagonists & inhibitors; Bacterial Proteins/genetics; Chromosome Mapping; DNA, Bacterial/analysis; Electron Transport Complex IV/genetics; Escherichia coli/genetics; Escherichia coli Proteins; Galactosidases/metabolism; Gene Expression Regulation, Bacterial; Iron-Sulfur Proteins/genetics; Operon/physiology; Repressor Proteins/antagonists & inhibitors; Repressor Proteins/genetics; Transcription, Genetic

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