PMID:8682793
| Citation |
Addinall, SG, Bi, E and Lutkenhaus, J (1996) FtsZ ring formation in fts mutants. J. Bacteriol. 178:3877-84 |
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| Abstract |
The formation of FtsZ rings (Z rings) in various fts mutants was examined by immunoelectron microscopy and immunofluorescence. In two temperature-sensitive ftsZ mutants which form filaments with smooth morphology, the Z ring was unable to form. In ftsA, ftsI, and ftsQ mutants, which form filaments with an indented morphology, Z rings formed but their contraction was blocked. These results indicate that fully functional ftsA, ftsQ, and ftsI genes are not required for Z-ring formation and are unlikely to have a role in localization of the Z ring. The results also suggest that one function of the Z ring is to localize the activity of other fts gene products. |
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| Keywords |
Bacterial Proteins/genetics; Bacterial Proteins/ultrastructure; Cytoskeletal Proteins; Escherichia coli/genetics; Escherichia coli/ultrastructure; Fluorescent Antibody Technique, Indirect; Genes, Bacterial; Microscopy, Immunoelectron; Mutation |
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