PMID:8590000
| Citation |
Pebay-Peyroula, E, Garavito, RM, Rosenbusch, JP, Zulauf, M and Timmins, PA (1995) Detergent structure in tetragonal crystals of OmpF porin. Structure 3:1051-9 |
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| Abstract |
The high-resolution structures of five porins have been solved by X-ray crystallography including the trigonal crystal form of the trimeric OmpF porin from Escherichia coli. In an accompanying article, the structure of the tetragonal form of OmpF porin is presented. In contrast to the trigonal crystal form, the protein surfaces normally in contact with lipids in the membrane are exposed and interact with amphiphiles in the tetragonal crystal. Thus, the tetragonal form can be used to investigate protein-detergent interactions. |
| Links | |
| Keywords |
Bacterial Outer Membrane Proteins/chemistry; Crystallization; Crystallography; Detergents/chemistry; Diamines/chemistry; Glucosides/chemistry; Models, Molecular; Neutron Activation Analysis/methods; Protein Conformation; Software |
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