PMID:8002604

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Citation

Sulavik, MC, Gambino, LF and Miller, PF (1994) Analysis of the genetic requirements for inducible multiple-antibiotic resistance associated with the mar locus in Escherichia coli. J. Bacteriol. 176:7754-6

Abstract

A series of novel genetic constructs derived from the marRAB operon was used to determine the role of this gene cluster in salicylate-inducible multiple-antibiotic resistance in Escherichia coli. Our findings indicate that regulated antibiotic resistance associated with this locus requires only the products of marR and marA, without any neighboring genes.

Links

PubMed PMC197238

Keywords

Bacterial Proteins/genetics; DNA-Binding Proteins; Drug Resistance, Microbial; Drug Resistance, Multiple/genetics; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Mutagenesis; Operon/genetics; Repressor Proteins/genetics

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