PMID:7988897

Citation	Uria-Nickelsen, MR, Leadbetter, ER and Godchaux, W 3rd (1994) Sulfonate-sulfur utilization involves a portion of the assimilatory sulfate reduction pathway in Escherichia coli. FEMS Microbiol. Lett. 123:43-8
Abstract	Strains of Escherichia coli lacking serine transacetylase or a positive regulator (Cys B protein) of the assimilatory sulfate reduction (ASR) pathway were unable to assimilate sulfonate-S, while single mutants in O-acetyl-L-serine sulfhydrylase (either 'A' or 'B') were able to do so. Mutants unable to reduce sulfate to sulfite were nonetheless able to form and accumulate sulfide and then cysteine from sulfonates, while strains lacking sulfite reductase were not. Thus terminal portions of the ASR pathway are involved in reduction of sulfonate-S to that of cysteine. E. coli K-12 formed cysteine more slowly, and accumulated lesser amounts of it with sulfonate-sulfur than it did from either sulfate or sulfite. These observations are consistent with our earlier report that sulfate is the preferred sulfur source when present simultaneously with a sulfonate.
Links	PubMed
Keywords	Acetyltransferases/genetics; Cysteine/metabolism; Cysteine Synthase/genetics; Escherichia coli/genetics; Escherichia coli/metabolism; Mutation; Oxidation-Reduction; Serine O-Acetyltransferase; Sulfates/metabolism; Sulfonic Acids/metabolism
edit table

Significance

You can help EcoliWiki by summarizing why this paper is useful

You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.

Add links to pages that link here (e.g. gene, product, method pages)

See Help:References for how to manage references in EcoliWiki.