PMID:7812713

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Citation

Sjöberg, BM (1994) The ribonucleotide reductase jigsaw puzzle: a large piece falls into place. Structure 2:793-6

Abstract

The three-dimensional structure of ribonucleotide reductase protein R1 from Escherichia coli reveals a novel 10-stranded alpha/beta barrel fold. A long loop penetrates the center cavity to assemble the active site cysteine triad.

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Keywords

Amino Acid Sequence; Binding Sites; Cysteine; Escherichia coli/enzymology; Models, Molecular; Protein Folding; Protein Structure, Secondary; Ribonucleotide Reductases/chemistry; Ribonucleotide Reductases/metabolism

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