PMID:7709428
| Citation |
Rao, BJ, Chiu, SK, Bazemore, LR, Reddy, G and Radding, CM (1995) How specific is the first recognition step of homologous recombination? Trends Biochem. Sci. 20:109-13 |
|---|---|
| Abstract |
The Escherichia coli RecA protein promotes homologous recognition in base triplets via non-Watson-Crick bonds that differ from those formed nonenzymically from DNA consisting of runs of purines or pyrimidines. Base substitutions reveal recognition to be permissive, consistent with a search for homology that achieves speed at the cost of precision. |
| Links | |
| Keywords |
Binding Sites; DNA/chemistry; DNA/metabolism; Rec A Recombinases/metabolism; Recombination, Genetic; Sequence Homology, Nucleic Acid |
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