PMID:7665504
| Citation |
Liu, X, Fujita, N, Ishihama, A and Matsumura, P (1995) The C-terminal region of the alpha subunit of Escherichia coli RNA polymerase is required for transcriptional activation of the flagellar level II operons by the FlhD/FlhC complex. J. Bacteriol. 177:5186-8 |
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| Abstract |
A number of transcription activators have been found to activate transcription via protein-protein contact between RNA polymerase alpha subunits and transcription factors; they are classified as class I factors. In this report, we demonstrate that the FlhD/FlhC complex, a transcription activator of the Escherichia coli flagellar regulon, requires the C-terminal domain of the RNA polymerase alpha subunit for transcription activation. We conclude that FlhD/FlhC is a class I transcription factor. |
| Links | |
| Keywords |
DNA-Binding Proteins/metabolism; DNA-Directed RNA Polymerases/metabolism; Escherichia coli/enzymology; Escherichia coli/genetics; Escherichia coli Proteins; Flagella/genetics; Gene Expression Regulation, Bacterial; Operon/genetics; Structure-Activity Relationship; Trans-Activators/metabolism; Transcription Factors/metabolism; Transcription, Genetic |
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