PMID:7635191

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Citation

Podkovyrov, S and Larson, TJ (1995) Lipid biosynthetic genes and a ribosomal protein gene are cotranscribed. FEBS Lett. 368:429-31

Abstract

By using insertional mutagenesis we demonstrated that the rpmF gene encoding ribosomal protein L32, the plsX gene encoding a protein involved in membrane lipid synthesis and several fatty acid biosynthetic genes (fabH, fabD and fabG) are cotranscribed. Organization of these genes into an operon may play a role in the coordinate regulation of the synthesis of ribosomes and the cell membranes.

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Keywords

3-Oxoacyl-(Acyl-Carrier-Protein) Synthase/genetics; Acyl-Carrier Protein S-Malonyltransferase; Acyltransferases/genetics; Alcohol Oxidoreductases/genetics; Bacterial Proteins/genetics; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins; Fatty Acid Synthetase Complex, Type II; Membrane Lipids/biosynthesis; Mutagenesis, Insertional; Ribosomal Proteins/genetics; Transcription, Genetic

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