PMID:7608098
| Citation |
Martin, RG, Nyantakyi, PS and Rosner, JL (1995) Regulation of the multiple antibiotic resistance (mar) regulon by marORA sequences in Escherichia coli. J. Bacteriol. 177:4176-8 |
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| Abstract |
The mar operon and adjacent sequences were subcloned on a low-copy-number plasmid to identify essential regulatory elements. A 1.1-kbp fragment containing 133 bp of the operator-promoter region (marO), the full marRA gene sequences, and only 10 of 72 marB codons provided a dela mar strain with normal repressibility and inducibility and the ability to beget mar constitutive mutants. |
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| Keywords |
Bacterial Proteins/genetics; DNA Mutational Analysis; DNA-Binding Proteins; Drug Resistance, Microbial/genetics; Drug Resistance, Multiple/genetics; Escherichia coli/genetics; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Mutagenesis; Operator Regions, Genetic/genetics; Promoter Regions, Genetic/genetics; Regulon/genetics; Repressor Proteins/genetics; Sequence Deletion; Transcription Factors/genetics |
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