PMID:7592359

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Citation

Rowsell, EH, Smith, JM, Wolfe, A and Taylor, BL (1995) CheA, CheW, and CheY are required for chemotaxis to oxygen and sugars of the phosphotransferase system in Escherichia coli. J. Bacteriol. 177:6011-4

Abstract

We carried out studies with Escherichia coli to determine the site at which the methylation-independent pathways for taxis to oxygen and to sugars of the phosphoenolpyruvate:sugar phosphotransferase transport system converge with the methylation-dependent chemotaxis pathways. Using genetic reconstitution of the pathways in a null strain, we determined that all pathways examined required the products of the genes cheA, cheW, and cheY. Thus, we conclude that both the methylation-independent and methylation-dependent pathways converge at CheA, the histidine kinase product of cheA.

Links

PubMed PMC177434

Keywords

Bacterial Proteins/genetics; Chemotaxis/genetics; Escherichia coli/drug effects; Escherichia coli/physiology; Escherichia coli Proteins; Fructose/pharmacology; Mannose/pharmacology; Membrane Proteins/genetics; Oxygen/pharmacology; Phosphoenolpyruvate Sugar Phosphotransferase System/metabolism; Signal Transduction/genetics

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