PMID:7482702

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Citation

Cooper, AA and Stevens, TH (1995) Protein splicing: self-splicing of genetically mobile elements at the protein level. Trends Biochem. Sci. 20:351-6

Abstract

Protein splicing is a newly discovered process that is the protein equivalent of RNA splicing. Protein splicing proceeds through a branched protein intermediate, and in vitro studies indicate that the reaction is autocatalytic. The excised 'intein' proteins are site-specific DNA endonucleases that catalyse genetic mobility of their DNA coding sequence by an 'intein homing' mechanism.

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PubMed

Keywords

Amino Acid Sequence; Molecular Sequence Data; Proteins/genetics; RNA Splicing

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