PMID:7045590
| Citation |
Shurvinton, CE and Lloyd, RG (1982) Damage to DNA induces expression of the ruv gene of Escherichia coli. Mol. Gen. Genet. 185:352-5 |
|---|---|
| Abstract |
Regulation of the ruv gene of E. coli was studied using phage Mud (Ap lac) to obtain a fusion of the lac genes to the ruv promoter. Beta-galactosidase synthesis in the ruv-lac fusion strain was induced by mitomycin C and other agents that damage DNA. The induction of beta-galactosidase could be altered by mutations either in lexA or recA from which it is concluded that ruv is regulated by lexA repressor. A possible function of ruv in promoting cell recovery following damage to DNA is discussed. |
| Links | |
| Keywords |
Bacterial Proteins/physiology; Coliphages/genetics; DNA Repair; DNA, Bacterial/radiation effects; Escherichia coli/genetics; Escherichia coli/radiation effects; Gene Expression Regulation; Genes, Bacterial; Rec A Recombinases; Recombination, Genetic; Serine Endopeptidases; Ultraviolet Rays |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.