PMID:7037404
| Citation |
Cole, ST (1982) Nucleotide sequence coding for the flavoprotein subunit of the fumarate reductase of Escherichia coli. Eur. J. Biochem. 122:479-84 |
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| Abstract |
The nucleotide sequence of the frdA gene, which encodes the flavoprotein subunit of the fumarate reductase, of Escherichia coli, has been determined. A polypeptide of Mr = 66,052, containing 602 amino acid residues, is predicted. In composition the FrdA protein strongly resembles the flavoprotein subunits of two succinate dehydrogenases. Moreover, a sequence of nine consecutive residues is common to the flavoprotein subunits from fumarate reductase and the beef heart succinate dehydrogenase. This sequence contains a histidyl residue which probably services as the site for attachment of the FAD cofactor to the reductase. |
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| Keywords |
Amino Acid Sequence; Bacterial Proteins/genetics; Base Sequence; Codon; Escherichia coli/enzymology; Flavoproteins/genetics; Genetic Code; Oxidoreductases/genetics; Oxidoreductases Acting on CH-CH Group Donors |
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