PMID:7010184
| Citation |
Jaurin, B, Grundström, T, Edlund, T and Normark, S (1981) The E. coli beta-lactamase attenuator mediates growth rate-dependent regulation. Nature 290:221-5 |
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| Abstract |
We have identified a new control or attenuator region in the chromosomal beta-lactamase operon of Escherichia coli. A single base alteration within its attenuator led to a loss in the cell's ability to coordinate its content of beta-lactamase with growth rate. We suggest a mechanism through which this mode of regulation operates. |
| Links | |
| Keywords |
Base Sequence; Cloning, Molecular; Escherichia coli/genetics; Escherichia coli/growth & development; Gene Expression Regulation; Genes, Regulator; Models, Genetic; Mutation; Operon; Plasmids; Protein Biosynthesis; Transcription, Genetic; beta-Lactamases/genetics; beta-Lactamases/metabolism |
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