PMID:6991489

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Citation

Campbell, A, Chang, R, Barker, D and Ketner, G (1980) Biotin regulatory (bir) mutations of Escherichia coli. J. Bacteriol. 142:1025-8

Abstract

Most mutants selected for derepression of the biotin operon required elevated concentrations of biotin for growth. Mutant extracts were deficient in holoenzyme synthetase activity.

Links

PubMed PMC294133

Keywords

Apoproteins/metabolism; Biotin/biosynthesis; Biotin/metabolism; Biotin/pharmacology; Carbon-Nitrogen Ligases; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli/metabolism; Genes, Regulator; Ligases/metabolism; Mutation; Repressor Proteins/biosynthesis

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