PMID:6988423
| Citation |
Garwin, JL, Klages, AL and Cronan, JE Jr (1980) Beta-ketoacyl-acyl carrier protein synthase II of Escherichia coli. Evidence for function in the thermal regulation of fatty acid synthesis. J. Biol. Chem. 255:3263-5 |
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| Abstract |
Cvc- mutants of Escherichia coli are deficient in the synthesis of cis-vaccenic acid and in the temperature control of fatty acid synthesis. In this communication, it is demonstrated that these mutants lack beta-ketoacyl-acyl carrier protein synthase II. The deficiencies in cis-vaccenate synthesis and synthase II are shown to be due to a lesion in the same gene, fabF. Lesions in the fabF gene are found to affect growth only when the strain also carries a lesion in the fabB gene, the structural gene for beta-ketoacyl-acyl carrier protein synthase I. |
| Links | |
| Keywords |
3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Escherichia coli/enzymology; Escherichia coli/genetics; Fatty Acids/biosynthesis; Genotype; Mutation; Phenotype; Species Specificity; Temperature; Transduction, Genetic |
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