PMID:6752127
Citation |
Lorowitz, W and Clark, D (1982) Escherichia coli mutants with a temperature-sensitive alcohol dehydrogenase. J. Bacteriol. 152:935-8 |
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Abstract |
Mutants of Escherichia coli resistant to allyl alcohol were selected. Such mutants were found to lack alcohol dehydrogenase. In addition, mutants with temperature-sensitive alcohol dehydrogenase activity were obtained. These mutations, designated adhE, are all located at the previously described adh regulatory locus. Most adhE mutants were also defective in acetaldehyde dehydrogenase activity. |
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Keywords |
Alcohol Dehydrogenase; Alcohol Oxidoreductases/genetics; Alcohol Oxidoreductases/metabolism; Drug Stability; Escherichia coli/enzymology; Escherichia coli/genetics; Kinetics; Mutation; Species Specificity; Temperature |
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