PMID:6752127

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Citation

Lorowitz, W and Clark, D (1982) Escherichia coli mutants with a temperature-sensitive alcohol dehydrogenase. J. Bacteriol. 152:935-8

Abstract

Mutants of Escherichia coli resistant to allyl alcohol were selected. Such mutants were found to lack alcohol dehydrogenase. In addition, mutants with temperature-sensitive alcohol dehydrogenase activity were obtained. These mutations, designated adhE, are all located at the previously described adh regulatory locus. Most adhE mutants were also defective in acetaldehyde dehydrogenase activity.

Links

PubMed PMC221556

Keywords

Alcohol Dehydrogenase; Alcohol Oxidoreductases/genetics; Alcohol Oxidoreductases/metabolism; Drug Stability; Escherichia coli/enzymology; Escherichia coli/genetics; Kinetics; Mutation; Species Specificity; Temperature

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