PMID:6421801
| Citation |
Chen, YM and Lin, EC (1984) Dual control of a common L-1,2-propanediol oxidoreductase by L-fucose and L-rhamnose in Escherichia coli. J. Bacteriol. 157:828-32 |
|---|---|
| Abstract |
Anaerobic growth of Escherichia coli on L-fucose or L-rhamnose as the sole source of carbon and energy depends on the regeneration of NAD from NADH by disposing the intermediate L-lactaldehyde as L-1,2-propanediol. The two parallel pathways, with their own permeases and enzymes encoded by two widely separated gene clusters, appear to share a single enzyme that catalyzes the formation of L-1,2-propanediol. Although this oxidoreductase is encoded by a gene at the fuc locus, the enzyme is inducible by both L-fucose and L-rhamnose. The inducibility by L-rhamnose is controlled by a gene at the rha locus with no other known functions, since the aerobic growth rate on L-rhamnose remains normal. L-1,2-Propanediol oxidoreductase activity is inducible only anaerobically, and the effect of the two methylpentoses operates at different levels: L-fucose exerts its influence post-transcriptionally; L-rhamnose exerts its influence transcriptionally. |
| Links | |
| Keywords |
Aerobiosis; Alcohol Oxidoreductases/biosynthesis; Anaerobiosis; DNA, Recombinant; Enzyme Induction; Escherichia coli/enzymology; Escherichia coli/genetics; Fucose/metabolism; Fucose/pharmacology; Gene Expression Regulation; Genes, Bacterial; Genes, Regulator; Mutation; Rhamnose/metabolism; Rhamnose/pharmacology; beta-Galactosidase/biosynthesis |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.