PMID:6393056
| Citation |
Aiba, H, Mori, K, Tanaka, M, Ooi, T, Roy, A and Danchin, A (1984) The complete nucleotide sequence of the adenylate cyclase gene of Escherichia coli. Nucleic Acids Res. 12:9427-40 |
|---|---|
| Abstract |
The complete nucleotide sequence of the cya gene from E. coli was determined. The gene encodes a polypeptide consisting of 848 amino acid residues with a calculated molecular weight of 97,542. The deduced protein structure reveals that cyclase is comprised of two domains, an amino-terminal region exhibiting catalytic activity and a carboxy-terminal region possibly carrying regulatory function. The frequent appearance of rare codons in the beginning of the gene as well as the sequence duplication in the promoter-initiator region suggest possible regulation(s) at the translational level. An unknown gene (cyaX) which seems to code for a very hydrophobic protein was found following the cya gene. Sequence analysis suggests that the cyax is a part of the cya operon. |
| Links | |
| Keywords |
Adenylate Cyclase/genetics; Amino Acid Sequence; Base Sequence; Codon; Escherichia coli/enzymology; Escherichia coli/genetics; Gene Expression Regulation; Genes; Genes, Bacterial; Operon; Protein Conformation |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
See also
References
See Help:References for how to manage references in EcoliWiki.