PMID:6102553
| Citation |
Diderichsen, B (1980) flu, a metastable gene controlling surface properties of Escherichia coli. J. Bacteriol. 141:858-67 |
|---|---|
| Abstract |
flu, a gene of Escherichia coli K-12, was discovered and mapped between his and shiA. It is shown that flu is a metastable gene that changes frequently between the flu+ and flu states. flu+ variants give stable homogeneous suspensions, are piliated, and form glossy colonies. flu variants aggregate, fluff and sediment from suspensions, are nonpiliated, and form frizzy colonies. flu+ and flu variants can be isolated from most strains. Implications of these observations are discussed, and it is demonstrated that flu+ variants of strain P678-54 yield three times more minicells than flu variants. |
| Links | |
| Keywords |
Chromosome Mapping; Escherichia coli/cytology; Escherichia coli/genetics; Escherichia coli/ultrastructure; Fimbriae, Bacterial/ultrastructure; Genes; Genetic Variation; Temperature |
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