PMID:6094504
| Citation |
Fishel, RA and Kolodner, R (1984) Escherichia coli strains containing mutations in the structural gene for topoisomerase I are recombination deficient. J. Bacteriol. 160:1168-70 |
|---|---|
| Abstract |
Mutations in the gene encoding topoisomerase I of Escherichia coli were tested for their effect on plasmid recombination. Recombination was decreased 1,000-fold at 30 and 37 degrees C and occurred at approximately wild-type frequencies at 42 degrees C. The suppression of topA mutations at 42 degrees C did not appear to be a result of increased topoisomerase I activity at 42 degrees C. |
| Links | |
| Keywords |
DNA Topoisomerases, Type I/genetics; Escherichia coli/enzymology; Escherichia coli/genetics; Genes; Genes, Bacterial; Genotype; Mutation; Plasmids; Recombination, Genetic |
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