PMID:5332864

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Citation

Pittard, J and Wallace, BJ (1966) Gene controlling the uptake of shikimic acid by Escherichia coli. J. Bacteriol. 92:1070-5

Abstract

Pittard, James (University of Melbourne, Melbourne, Australia), and B. J. Wallace. Gene controlling the uptake of shikimic acid by Escherichia coli. J. Bacteriol. 92:1070-1075. 1966.-Mutants possessing an impaired ability to take up exogenously supplied shikimic acid were isolated. Mutants showing either a complete or partial loss of this activity were found. The mutations have been mapped on the Escherichia coli chromosome and occur in a single gene, situated near to the cluster of genes concerned with histidine biosynthesis. The uptake of dehydroshikimic acid was also affected by these mutations, suggesting a common mechanism for the uptake of these two related intermediates of aromatic biosynthesis.

Links

PubMed PMC276380

Keywords

Carbon Isotopes/diagnostic use; Chromosomes; Escherichia coli/metabolism; Genes; Mutation; Shikimic Acid/metabolism

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