PMID:4919746
| Citation |
Cox, GB, Gibson, F, Luke, RK, Newton, NA, O'Brien, IG and Rosenberg, H (1970) Mutations affecting iron transport in Escherichia coli. J. Bacteriol. 104:219-26 |
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| Abstract |
A mutant of Escherichia coli K-12 unable to form an essential component of the enterochelin-dependent iron transport system has been isolated. This strain carries a mutation in a gene designated fep, mapping close to two genes, entA and entD, concerned with enterochelin synthesis. Strain AN102, which carries the fep(-) allele, accumulates large quantities of enterochelin and gives a growth response to sodium citrate. The cytochrome b(1) and total iron content, and the measurement of the uptake of (55)Fe(3+), indicate an impairment of the enterochelin-dependent iron transport system. The growth response to sodium citrate is related to the presence, in strain AN102, of an inducible citrate-dependent iron transport system. |
| Links | |
| Keywords |
Biological Transport; Chromosome Mapping; Citrates/metabolism; Cytochromes/metabolism; Escherichia coli/growth & development; Escherichia coli/metabolism; Genes; Genetics, Microbial; Iron/metabolism; Iron Isotopes; Mutation; Transduction, Genetic |
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