PMID:4145959

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Citation

Burke, WF, Swafford, JR and Reeves, HC (1973) Crystallization of NADP-specific isocitrate dehydrogenase. Science 181:59-60

Abstract

The first crystalline preparation of isocitrate dehydrogenase specific for nicotinamide adenine dinucleotide phosphate has been obtained with enzyme isolated from Escherichia coli. Scanning electron microscopy was employed to elucidate the structure of the crystals, which were found to exist as regular octahedrons ranging in size from 5 to 90 micrometers.

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Keywords

Crystallization; Escherichia coli/enzymology; Isocitrate Dehydrogenase/isolation & purification; Methods; Microscopy; Microscopy, Electron, Scanning; Molecular Conformation; NADP

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