PMID:4043336

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Citation

Kamiya, H, Muramoto, K, Hoshino, T and Raj, U (1985) Isolation and characterization of hemagglutinins from the sponge Dysidea herbacea. Experientia 41:1201-2

Abstract

The sponge Dysidea herbacea (Keller) was found to possess hemagglutinins. The major component, DHA-I, is a protein with a mol. wt of 26,000, which dissociates into subunits of equal size (14,000). It contains large amounts of glutamic acid and aspartic acid residues, but no half-cystine, methionine or histidine residues. DHA-I reacted with rabbit and human AB0 erythrocytes. D-galactose and lactose were effective inhibitors of DHA-I. The sponge also contained a minor component(s) which reacted preferentially with rabbit erythrocytes but not with human AB0 erythrocytes.

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Keywords

Amino Acids/analysis; Animals; Hemagglutination Inhibition Tests; Hemagglutinins/analysis; Humans; Macromolecular Substances; Molecular Weight; Porifera; Rabbits

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