PMID:3915782
| Citation |
Evan, GI, Lewis, GK, Ramsay, G and Bishop, JM (1985) Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5:3610-6 |
|---|---|
| Abstract |
Six monoclonal antibodies have been isolated from mice immunized with synthetic peptide immunogens whose sequences are derived from that of the human c-myc gene product. Five of these antibodies precipitate p62c-myc from human cells, and three of these five also recognize the mouse c-myc gene product. None of the antibodies sees the chicken p110gag-myc protein. All six antibodies recognize immunoblotted p62c-myc. These reagents also provide the basis for an immunoblotting assay by which to quantitate p62c-myc in cells. |
| Links | |
| Keywords |
Antibodies, Monoclonal/isolation & purification; Antibody Specificity; Cell Line; Humans; Immunoassay; Peptide Fragments/chemical synthesis; Peptide Fragments/immunology; Proto-Oncogene Proteins/analysis; Proto-Oncogene Proteins/immunology; Proto-Oncogene Proteins c-myc |
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