PMID:3901876

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Citation

Dassa, E and Hofnung, M [Homologies between integral proteins of the inner membrane of binding protein transport systems in enterobacteria]. Ann. Inst. Pasteur Microbiol. 136A:281-8

Abstract

Binding protein-dependent transport systems from Enterobacteriaceae comprise a periplasmic binding protein and three proteins associated with the inner membrane. Of these, two appear to be integral membrane proteins. We describe here a sequence which is highly conserved between these two proteins in the case of the system for maltose transport in Escherichia coli. This sequence is also present in all of the known integral membrane proteins from binding protein-dependent transport systems. It is remarkable that this sequence is located at a constant distance of approximatively 90 residues from the COOH-terminal ends of these proteins. Some implications of these observations are discussed.

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Keywords

Amino Acid Sequence; Biological Transport, Active; Carrier Proteins/metabolism; Chemical Phenomena; Chemistry; Enterobacteriaceae/metabolism; Escherichia coli/metabolism; Maltose/metabolism; Membrane Proteins/metabolism

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