PMID:374336
| Citation |
Lutkenhaus, JF and Donachie, WD (1979) Identification of the ftsA gene product. J. Bacteriol. 137:1088-94 |
|---|---|
| Abstract |
A nonsense mutation was identified in the essential cell division gene ftsA of Escherichia coli. A gamma-transducing phage was isolated which complemented this mutation. This phage programmed the synthesis of four bacterial proteins in UV-irradiated cells. By substituting the nonsense mutation for the ftsA+ allele in this transducing phage and comparing the proteins programmed by it in UV-treated Su+ and Su- cells, the product of the ftsA gene was identified as a protein with a molecular weight of 50,000. |
| Links | |
| Keywords |
Alleles; Bacterial Proteins/analysis; Cell Division; Coliphages/genetics; Escherichia coli/analysis; Escherichia coli/genetics; Escherichia coli/radiation effects; Genes; Molecular Weight; Mutation; Transduction, Genetic; Ultraviolet Rays |
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